Abstract Impairment of inferior olivary neurons (IONs) affects whole-body movements and results in abnormal gait and posture.Because IONs are activated by unpredicted motion rather than regular body movements, the postural dysfunction caused by ION lesions is expected to involve factors other than simple loss of feedback control.In this study, we m
Leprosy, caused by Mycobacterium leprae (M.leprae), is treated with a multidrug regimen comprising Dapsone, Rifampicin, and Clofazimine.These drugs exhibit bacteriostatic, bactericidal and anti-inflammatory properties, respectively, and control the dissemination of infection in the host.However, the current treatment is not cost-effective, does not
Thymoquinone, an active compound isolated from black cumin seeds (Nigella sativa L.), has pharmacological activity as anticancer, antiinflammatory, and immunomodulator.This compound has a volatile nature, easily oxidized, and low melting point, leading to difficulties in tablet formulation.Moreover, its low solubility in water leading to low bioava